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Tenover,
Clinical Assistant Professor, Affiliated Palo Alto VA Health Care System 3801 Miranda Avenue (GRECC 182B) Palo Alto, California 94304 Telephone: 650-493-5000, ext. 66946 Email: [email protected]
Professional Snapshot

Administrative Appointments
Clinical Professor of Medicine (Affiliate), General Internal Medicine/Gerontology and Geriatric Medicine, Stanford University School of Medicine, Stanford, CA, 2009-present Professor Emeritus, Emory University, Atlanta, GA, 1990-1994 Honors & Awards
Emory University Department of Medicine Outstanding Service Award, 2005 Winner of best clinical research manuscript, Journal of Clinical Endocrinology and Metabolism, 2004 American Society of Andrology Distinguished Service Award, 2004 Selected for America's Top Doctors, 2001-2009 Atlanta's Top Doctors, 2002, 2005, 2007 Education & Community
Professional Education
Geriatrics Fellow, University of Washington, Department of Medicine, Division of Gerontology and Geriatric Medicine, Veterans Administration Medical Center, Grecc, Seattle, WA, 1985-1987 Advanced Subspecialty Resident in Geriatrics, University of Washington, Veterans Administration Medical center, Seattle, Washington, 1984-1985 Chief Medical Resident, University of Washington, Veterans Administration Medical Center, Seattle, Washington, 1983-1984 Scientific Focus
Myers JS, and Hardman JK: Formaldehyde-induced cross-linkages in the alpha subunit of E.coli tryptophan synthetase. J Biol Chem. 246: 3863-3969, l971 Myers JS, and Jakoby WB: Effect of polyhydric alcohols on kinetic parameters of enzymes. Biochem Biophys Res Commun. 51: 631-636, l973 Myers JS, and Jakoby WB: Glycerol as an agent eliciting small conformational changes in alcohol dehydrogenase. J Biol Chem.250: 3785-3789, l975 CURRICULUM VITAE
JOYCE S. (LISA) TENOVER, M.D., Ph.D. Associate GRECC Director for Clinical Services VA Palo Alto Health Care System Palo Alto, CA 94304 [email protected] A.B., Chemistry-Duke University, Durham, NC Ph.D., Biochemistry- The Johns Hopkins University, Baltimore, MD POSTDOCTORAL RESEARCH ASSOCIATE--Georgetown University, School of Biochemistry, Washington, D.C. Washington University Medical School, Washington,D.C. INTERNSHIP / RESIDENCY-University of Washington, Department of Medicine, CHIEF MEDICAL RESIDENT-University of Washington, Veterans Administration Medical Center, Seattle, WA 1984-1985 ADVANCED SUBSPECIALTY RESIDENT IN GERIATRICS, University of Administration Medical Center, Seattle, WA. GERIATRICS FELLOW - University of Washington, Department of Medicine, Division of Gerontology and Geriatric Medicine, Veterans Administration ACADEMIC APPOINTMENTS ACTING INSTRUCTOR, University of Washington, Department of Medicine, Division of Gerontology and Geriatric Medicine, Seattle, WA. 1987-1990 ASSISTANT University of Washington, Department of Medicine, Division of Gerontology and Geriatric Medicine, Seattle, WA. ASSISTANT PROFESSOR, Emory University, Department of Medicine, Division of Geriatric Medicine and Gerontology, Atlanta, GA. ASSOCIATE PROFESSOR, (With Tenure) Emory University, Department of Medicine, Division of Geriatric Medicine and Gerontology, Atlanta, GA. PROFESSOR (with Tenure), Emory University, Department of Medicine, Division of Geriatric Medicine and Gerontology, Atlanta, GA Emory University, Atlanta, GA OF MEDICINE (Affiliate), General Internal Medicine/ Medicine, Stanford University School of Medicine, Stanford, CA OTHER PROFESSIONAL EXPERIENCE Medical Traineeship Director, Northwest Geriatric Education Center, Seattle, WA. Director, Harborview Medical Center SeniorCare Outreach Clinics, Seattle, WA. Director of Education, Division of Gerontology and Geriatric Medicine, Emory Univ 1990-1997 Director, Continence Clinic, Wesley Woods Geriatric Hospital, Atlanta, GA Director, Geriatric Fellowship Program, Emory University SOM, Atlanta, GA 1997-2000 Co-Director, Fellowship Program, Emory University SOM, Atlanta, GA 2003-2007 Co-Director, Wesley Woods Outpatient Clinic, Atlanta, GA Clinical Research Team Service Performance Team Emory HealthCare Contract Pricing Team Chief of Medicine, Wesley Woods Hospital, Atlanta, GA Medical Co-Director, Wesley Woods Long Term Hospital, Atlanta, GA Associate Division Director, Clinical Programs; Emory Division of Geriatric Medicine Medical Service Quality Officer, Wesley Woods Hospital, Atlanta, GA BOARD CERTIFICATIONS National Board of Medical Examiners Board of Internal Medicine, Diplomate, Subspecialty Board-Geriatric Medicine, American Board of Internal recertification 1997; recertification 2008 Medical License--Washington State (#0019239); inactive/allowed to lapse 1990-8/31/09 Medical License--Georgia (#033725); inactive/allowed to lapse License—California HONORS AND AWARDS 2002,2005,2007 Atlanta's Top Doctors Selected for America's Top Doctors American Society of Andrology Distinguished Service Award Winner of best clinical research manuscript, Journal of Clinical Endocrinology and Metabolism Emory University Department of Medicine Outstanding Service Award 1990,1991,1997Nominating Committee, American Society of Andrology of Andrology Postgraduate Course Chairman, Constitution and Bylaws Committee, American Society of Andrology Executive Council, American Society of Andrology President, American Society of Andrology 2001-2003 Chairman, Committee, American Society of Andrology 2003-2004 ABIM-CPD Geriatric Endocrinology Committee Co-Chair, Physician Advisory Committee, Georgia Medicare Health Support Program B. Institutional Medical Resident Rotation Evaluation Committee 1985-1987 Patient Northwest Geriatric Education Center, Executive Committee Search Committee, Chief of Medical Service, Harborview Medical Center, Seattle WA Alzheimer's Disease Center Education Committee Medical School Admissions Committee Internal Medicine House Staff Evaluation Committee Wesley Woods Ethics Committee Wesley Woods Strategic Planning Committee Executive Committee for Center of Geriatrics Clinical Safety Steering Committee Emory HealthCare Clinical Performance Team Search Committee for Department Chair of PM&R Search Committee for Administrative Director of Pharmaceutical Services for Emory Healthcare Chair, Pharmacy and Therapeutics Committee, Wesley Woods Hospital Progress and Promotions Committee, Physician Assistant Program 1993-2008 Professional Committee, Wesley Woods Steering Committee, Southeast Center for Excellence in Geriatric Medicine Geriatric Fellowship Committee 2001-2008 Credentials Committee, Wesley Woods Center Emory Health Sciences Center Program and Facility Planning Group 2007-2008 EmoryHealthCare Formulary Advisory Group PROFESSIONAL SOCIETIES (CURRENT) American College of Physicians, Fellow American Geriatrics Society American Society of Andrology International Society for Study of the Aging Male TRAINEE TEACHING Medical students:
Coordinator, GGM-1 Course, Wesley Woods Hospital Sophomore Clinical Methods. Emory School of Medicine Junior Student Lectures, Lecturer; Emory School of Medicine Medical Pharmacology Course, Lecturer; Emory School of Medicine Bedside Teaching Rounds, Wesley Woods Hospital Problem based learning preceptor, Emory School of Medicine Internal Medicine Residents:
Attending Physician, Medical Service, Grady Memorial Hospital, Atlanta, GA Lecturer, Resident Conferences at VAMC, Grady, Emory University Hospital Lectures, Wesley Woods Hospital Bedside Teaching Rounds, Wesley Woods Hospital 1990-2008 Attending Physician/Clinical teaching, Medical Service, LTAC Service, and Consult Service, Wesley Woods Hospital 1995-1998, 2002-2005) Geriatric Outpatient Clinic Attending, Wesley Woods Outpatient Service, Emory Senior Resident Physical Exam Evaluator PGY-2/3 Workshop: Transitions in Care; Co-Director and presenter Geriatrics Theme Month lecturer Graduate program (Geriatric Medicine Fellows):
SCEGM seminar presenter Core Curriculum, Geriatric Medicine Fellowship Program, Emory School of Medicine Bedside Teaching Rounds, Wesley Woods Hospital 1998-200 Long Term Care Teaching Rounds, Wesley Woods Center 1990-2008 Attending Physician/Clinical teaching, Medical Service, LTAC Service, and Consult Service, Wesley Woods Hospital Interdisciplinary Care Conferences, Wesley Woods Hospital Geriatric Medicine Journal Club; director and presenter, Emory Healthcare Physicians Assistant Students Human Sexuality Course, Lecturer; Emory University Physicians Assistant Students Pharmacology Course, Lecturer, Emory University Physician Assistant Physical Exam Course, mentor 2004-2007 Geriatric Emergency Medicine Residents Mentor, Physician Assistant students who rotated at Wesley Woods Hospital UNIVERSITY RELATED NONTRAINEE EDUCATION (other than lectures at CME courses, annual medical meetings, and University Medical Grand Rounds): Ethics Grand Rounds presenter, Wesley Woods Center Day in Columbus lectures and bedside teaching 1995, 2001, 2006, Medical Utilization course lecture 1990-1998, 2004, 2006 Emory Senior University speaker LECTURESHIPS, CONFERENCE SPEAKER, SEMINAR INVITATIONS (outside home institution; last 7 years) VII International Congress of Andrology, Montreal, Canada, June 2001. "Benefits and Risks of Testosterone in Aging Men" Urology Grand Rounds, Medical College of Georgia, Augusta, October 2001. "Male Hormone Trilogy Lecture, The 17th World Congress on Fertility and Sterility, Melbourne, Australia, November 2001. "Hormone Replacement Therapy for Men" Department of Gynecology Grand Rounds, University of Florida, Gainesville, March 2002, "Andropause, Overview and Update" Plenary Lecture, Annual Meeting of the American Society of Andrology, Seattle, WA, April 2002, "Androgen Therapy in the Older Man - Where are we Now and Where are We Going? Primary Care Update, University of South Florida, Tampa, FL, September 2002, "Andropause and Male Mid-Atlantic Section of the American Urological Association, Baltimore, MD, October 2002, "Andropause:Clinical Endocrine Grand Rounds, University of Miami, FL, November 2002, "Testosterone Therapy in Older Men: Multidisciplinary Endocrine Conference, University of Louisville, KY, February 2003, "Testosterone Deficiency in Aging Men: Is There a Role for Hormone Replacement Therapy?" 2nd Annual Geriatric Symposium for Primary Care Providers, University of South Carolina School of Medicine, Columbia, SC, February 2003, "Male Hormone Replacement Therapy: A Clinical Update". 27th Mexican Urological Congress, Morelia, Mexico, March 2003, "Andropause" Institute of Medicine Workshop, Phoenix, AZ, March 2003, "Bone related outcomes in testosterone Medical Grand Rounds, Lakewood Hospital, Cleveland OH, May 2003, "Andropause". National Conference of the American Academy of Nurse Practitioners, Anaheim CA, June 2003, Fact or fantasy?" Virginia Geriatrics Society Program: Men's Midlife Health, Richmond VA, September 2003, "Who should receive testosterone supplementation and how?" 7th International Conference on Geriatric Nephrology and Urology, Atlanta GA, October 2003, "Male hormone therapy: potential benefits vs potential urogenital risks" Research Service Seminar, VA Medical Center, Seattle, WA, January 2005: Androgen replacement therapy in the elderly man: Promise or Disappointment? Department of Pharmacology Conference, McGill University, Montreal, Canada, February 2005: An update on male hormone replacement for the older man. 2005 National Conference on Men's Health, Altanta, GA,: Is there a role for hormone replacement Urology Update Conference, Atlanta, GA, December 2005: Osteoporosis in men Fit to Frail: Issues in Mens' Health, Conference, St. Petersburg, FL, February 2006: Should we offer to older hypogonadal men? Issues in Male Sexual Health: From Bench to Bedside. ASA Postgraduate Course, Chicago, IL, April 2006: (1) Male hormone replacement therapy and the prostate; (2) Androgens and the aging male: issues regarding mood, cognition, and replacement. Gordon Conference on Reproductive, New London CT, June 2006: "The Aging Male Reproductive Axis" Endocrine Society National Meeting, Clinical Debate, Boston MA, June 2006: "Should We Offer Hormone Replacement Therapy to Aging Men ? Con" Gwinnett Medical Center Endocrinology Conference, Lawrenceville GA, October 2006: "Hormone Replacement Therapy for the Older Man: Clinical Update". Advances in Urology 2006 (CME Course), Altanta, GA, December 2006: "Consequences of Androgen Deprivation Therapy in Prostate Cancer". VAMC GRECC Conference, Palo Alto, CA, June 2008: "Testosterone Replacement Therapy in Older or Disappointment?" American Society of Andrology Annual Meeting, Philadelphia PA, April 2009: "Testosterone and Bone" Medical Grand Rounds, Kaiser Permanente Santa Clara, June 2009. "Hormone Replacement Therapy in the Older Man" EDITORIAL REVIEW RESPONSIBILITIES Journal of Andrology (1994-1996) International Journal of Andrology, Journal of Clinical Endocrinology & Metabolism, Journal of Gerontology, Journal of the American Geriatrics Society GRANT REVIEWS / ADVISORY BOARDS: Member, Geriatric and Rehabilitative Medicine Special Emphasis Panel, NIA, NIH. Ad hoc reviewer, Claude Pepper Program Projects, NIH. Ad hoc reviewer, GCRCs, NIH Member, Geriatric and Rehabilitative Medicine Study Section (GRM), NIA, NIH External Advisory Board, Sarcopenia Program Project, Mayo Clinic, Rochester MN Ad hoc reviewer, GRM, NIA, NIH Participant, American Board of Internal Medicine CPD project for integrating Geriatrics into subspecialties of Internal Medicine Safety Monitoring Board (DSMB), Claude Pepper OAIC, University of Texas Medical Branch,Galveston, TX DSMB, NIH Grant "Improving Sleep in Nursing Homes", Emory University and Hardman JK: Formaldehyde-induced cross-linkages in the alpha subunit of E. coli tryptophan synthetase. J Biol Chem. 246: 3863-3969, l971. Myers JS, and Jakoby WB: Effect of polyhydric alcohols on kinetic parameters of enzymes. Biochem Biophys Res Commun. 51: 631-636, l973. Myers JS, and Jakoby WB: Glycerol as an agent eliciting small conformational changes in alcohol dehydrogenase. J Biol Chem.250: 3785-3789, l975. Myers JS, and Gabriel O: Specific conversion of galactose to galacturonic acid in glycoproteins: method for carbohydrate linkage analysis. Carbohydrate Res. 67: 223-234, 1978. Tenover JS, Dahl KD, Hseuh AJW, Lim P, Matsumoto AM, and Bremner WJ: Bioactive and immunoreactive follicle-stimulating hormone levels and the response to clomiphene in healthy young and elderly men. J Clin Endocrinol Metab. 64: 1102-1108, l987. Tenover JS, Matsumoto AM, Plymate SR, and Bremner WJ: The effects of aging in normal men on bioavailable testosterone and luteinizing hormone secretion: response to clomiphene citrate. J Clin Endocrinol Metab. 65: 1118-1126, l987. Tenover JS, McLachlan RI, Burger HG, deKretser DM, and Bremner WJ: Decreased serum in normal elderly men: Evidence for a decline in Sertoli cell function with aging. J Clin Endocrinol Metab. 67: 455-459, l988. Tenover JS, Matsumoto AM, Clifton DK, and Bremner WJ: Age-related alterations in the circadian rhythms of pulsatile luteinizing hormone and testosterone secretion in healthy men. J Gerontol Med Sci. 43: M163-M169, l988. Sheckter CB, McLachlan RI, Tenover JS, Matsumoto AM, Burger HG, deKretser DM, and Bremner WJ: Stimulation of serum inhibin concentrations by gonadotropin-releasing hormone in men with idiopathic hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 67: 1221-1224, l988. Plymate SR, Tenover JS, and Bremner WJ: Circadian variation in testosterone, sex hormone binding globulin, and calculated non-sex hormone globulin bound testosterone in healthy young and elderly men. J Androl. 10: 366-371, l989. JS, Dahl KD, Vale WW, Rivier JS, and Bremner WJ: Hormonal responses to a potent hormone- releasing hormone antagonist in normal elderly men. J Clin Endocrinol Metab. 71: 881-888, l990. JS, and Bremner WJ. The effects of normal aging on the response of the pituitary-gonadal axis to chronic clomiphene administration in men. J Androl. 12:258-263, 1991. JS, and Bremner WJ. Circadian rhythm of serum immunoreactive inhibin in young and Gerontol Med Sci. 46: M181-184, 1991. Stoner E, and Finasteride Study Group. The clinical effects of 5a-reductase inhibitor, finasteride, prostatic hyperplasia. J Urol. 147:1298-1302, 1992. Tenover JS. Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab. 75:1092-8, 1992. Gormley GJ, Stoner E, Bruskewitz RC, Imperato-McGinley J, Walsh PC, McConnell JD, Andriole GL, Geller J, Bracken BR, Tenover JS, Vaughan DE, Pappas R, Taylor A, Binkowitz B, and Ng J. The effect of finasteride in men with benign prostatic hyperplasia. N Engl J Med. 327:1185-91, 1992. Stoner E, and Finasteride Study Group. Maintenance of clinical efficacy with finasteride therapy for 24 months in patients with benign prostatic hyperplasia. Arch Intern Med 154:83-89, 1994. Stoner E, and Finasteride Study Group: Three-year safety and efficacy data on the use of finasteride in the treatment of benign prostatic hyperplasia. Urology 43:284-94, 1994. Martins HF, Sheets PK, Tenover JS, Dugowson CE, Bremner WJ, Starkebaum G: Decreased testosterone levels in men with rheumatoid arthritis: effect of low-dose prednisone therapy. J Rheum 21:1427-31, 1994. Moore E, Bracken B, Bremner W, Geller J. McConnell J, Roy J, Tenover JS, Vaughn D, Pappas F, Cook T, Gormley GJ, and Stoner E. Proscar: Five-year experience. Eur Urol 28:304-9, 1995. JL: Testosterone and the Aging Male. J. Androl, 18:103, 1997. JL: Pagano GA, Morton AS, Liss CL, and Byrnes CA: Efficacy and tolerability of finasteride in symptomatic benign prostatic hyperplasia: A primary care study. Clin Therap 19:243-258, 1997. Byrnes CA, Liss CL, Tenover JL, Lippert MC, Gillenwater JY: Combined analysis of two multicenter studies of finasteride 5mg in the treatment of symptomatic benign prostatic hyperplasia Prostate Cancer Prost Dis 1:26-31, McConnell JD and the Finasteride Long -Term Efficacy and Safety Study Group. The effect of the risk of acute urinary retention and the need for surgical treatment among men with benign prostatic hyperplasia. N Eng J Med 338;557-63, 1998. Bhasin S, Bagatell CJ, Bremner WJ, Plymate SR, Tenover JL, Korenman SE, Nieschlag E. Therapeutic perspective: Issues in testosterone replacement in older men. J Clin Endocrinol Metab 83:3435-3448, 1998. Tenover L: Experience of testosterone replacement in the elderly. Mayo Clin Proc, 75:577-82, 2000. Tenover JL: Testosterone Replacement Therapy in Older Men. Natl J Androl. 7:141-146 (2001). Matsumoto AM, Tenover L, McClung M, et al.: The long-term effect of specific type II alpha- eductase inhibition with finasteride on bone mineral density in men: results of a 4-year, placebo-controlled trial. J Urol, 167:2105-8 (2002) Okun MS, Walter BL, McDonald WM, Tenover JL, Green J, Juncos JJ, DeLong MR. Beneficial effects of testosterone replacement for the nonmotor symptoms of Parkinson Disease. Arch Neurol, 59:1750-3 (2002). Wessells, H, Roy J, Bannow J, Grayhack, Matsumoto A, Tenover L, et al. Incidence and severity of sexual adverse experiences in finasteride and placebo treated men with benign prostatic hyperplasia. Urology 61: 579-584 (2003). 31. Tenover JS. Declining testicular function in aging men. Intl J Impotence Res 15(4):S3-8 (2003). 32. Amory JK, Watt NB, Easley KA, Sutton PR, Anawalt BD, Matsumoto AM, Bremner WJ, Tenover JL. Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone. J Clin Endocrinol Metab 89:503-10 (2004). [**Winner of the prize for best clinical research paper in the J Clin Endocrinol Metab for 2004] Page ST, Amory JK, Bowman FD, Anawalt BD, Matsumoto AM, Bremner WJ, Tenover JL. exogenous testosterone (T) alone or T with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T. J Clin Endocrinol Metab 90:1502-1 Calof OM, Singh AB, Lee ML, Kenny AM, Urgan RJ, Tenover JL, Bhasin S. Adverse events associated with testosterone replacement in middle-aged and older men: a meta-analysis of randomized, placebo-controlled trials. J Gerontol Med Sci 60A:1451-7 (2005) O'Donnell AB, Travison TG, Harris SS, Tenover JL, McKinlay JB. Testosterone, dehydroepi- androsterone and physical performance in older men: results from the Massachusetts male aging study. J Clin Endocrinol Metab 91:425-31 (2006). 36. Vaughan C, Goldstein FC, Tenover JL. Exogeneous testosterone alone or with finasteride does not improve measurements of cognition in healthy older men with low serum testosterone. J Androl 28:875-82 (2007). Eskildsen M, Price T, Tenover JL. Computer-based geriatrics workbooks for resident teaching. MedEdPORTAL;http://services.aamc.org/isp/mededportal/retrieveSubmissionDetailByld.do?subId=640. 2007 38. Johnson TM, Burrows PK, Kusek JW, Nyberg LM, Tenover JL, Lepor H, Roehrborn CG. The effect of doxazosin, finasteride, and combination therapy on nocturia in men with benign prostatic hyperplasia, J Urol 178:2045-51 (2007). 39. Tenover J, Flacker J. Ohuabunwa U. Care Transitions in the Older Adult. MedEdPORTAL; BOOK CHAPTERS AND REVIEWS Myers JS, and Bremner WJ: Hormonal aspects of reproductive and sexual function in aging men.IN: L Dennerstein and I Fraser (Eds). Proceedings of the Eighth International Congressof Psychosomatic Obstetrics and Gynecology, Elsevier Science Publishing, Excerpta Medica, New York, 389-395, l986. Bremner WJ, Myers JS, and Matsumoto AM: Episodic LH secretion in normal men. IN: Episodic Hormone Secretion, WF Crowley and JG Hofler (Eds), John Wiley and Sons, New York, Bremner WJ, Myers JS, and Matsumoto AM: La secrezione episodica di LH negli uomini normali. IN: Bioritmi Endocrini Fisiologia, Diagnostica ed Applicazioni Terapeutiche, M Filicori, CL Flamigni, and WF Crowley (Eds), CIC Press, Bologna, 153-160, l988. McLachlan RI, Robertson DM, Healy DL, Soules MR, Bremner WJ, Matsumoto AM, Tenover JS, Forage RG, Findlay JK, Burger HG, and deKretser DM: Studies on the structure and physiology of inhibin. IN: Horizons in Endocrinology, M Maggi, CA Johnson (Eds), Serono Symposium Publications, Raven Press, New York, Vol 52: 43-61, l990. Bremner WJ, Bagatell CJ, McLachlan RT, Matsumoto AM, Tenover JS, and Soules MR: Central inhibin secretion in human beings. IN: Neuroendocrine Regulation of Reproduction, SSC Yen and WW Vale (Eds), Serono Symposia USA, Norwell MA, 189-193, Prostates, pates, and pimples: the potential medical uses of steroid 5 - reductase inhibitors. IN: Endocrinology and Metabolism Clinics of North America., JF Strauss (Ed.), WB Saunders, Philadelphia, Vol 20 (4), 893-909,1991. Tenover JS. Male hormonal changes with aging. IN: Endocrinology and Metabolism in the Elderly. JE Morley and SG Korenman (Eds). Blackwell Scientific Publications, Boston ; 243-261, Pharmacologic Therapy for Benign Prostatic Hyperplasia. IN: Current Management of Benign Prostatic Hyperplasia , American Journal of Medicine, Continuing Education Series. M. O'Leary, R. Roberts (Eds). Cahners Healthcare Communications, Belle Mead, NJ; 11-15, 1994. JS: Androgen administration to aging men. IN: Endocrinology & Metabolism Clinics of North America. WJ Bremner (Ed.), WB Saunders, Philadelphia , Vol. 23 (4), 877-92, 1994. J: Androgen Therapy in Aging Men. IN: Pharmacology, Biology, and Clinical Applications of Androgens. S. Bhasin, R. Swerdloff, C. Wang (Ed.), John Wiley & Sons, New York 309-318, 1996. JL: Effects of Androgen Supplementation in the Aging Male. IN: Androgens and the Aging B Oddens and A Vedrmeulen (Eds). The Parthenon Publishing Group, London; 191-204, 1996. JL: Androgen Deficiency in Aging Men. IN: Current Advances in Andrology, GMH Frick, GWH Baker (Eds) Monduzzi Editore, Bologna, Italy; 285-288, 1997. Bhasin S, Tenover JS: Editorial: Age-associated sarcopenia-issues in the use of testosterone as agent in older men. J Clin Endocrinol Metab 82:1659-60, 1997. The male climacteric: fact or fiction? IN: Erectile Dysfunction. A. Morales (Ed). Martin Duntiz, London, 39-48, 1998. JL: Male hormone replacement therapy including "andropause" IN: Endocrinol Metab Clinic N. Amer, H.C. Burger, R.I. McLachlan (Eds). W.B. Saunders Co. Philadelphia, Vol 27 (4), 969-987, 1998. JL: Aging and male sexual function. IN: Handbook of Sexual Dysfunction, W.J.G.Hellstrom (ed), The American Society of Andrology, Allen Press, Inc. Lawrence, Kansas, 39-42, 1999. JL: Trophic factors and male hormone replacement. IN: Principles of Geriatric Medicine and Gerontology, 4th Edition. W. Hazzard, J.P. Blass, W.H. Ettinger, J.B. Halter, J. G.Ouslander (Eds), McGraw Hill, New York, 1029-1040, 1999. Tenover JS: Androgen replacement therapy to reverse and/or prevent age-associated sarcopenia in men. IN: Bailliere's Clinical Endocrinology and Metabolism, S. Bhasin (Ed), Bailliere Tindall, London, Vol 12 (3), 419-425, Tenover JL: Testosterone and the Older Man. IN: Hormone Replacement Therapy. W. Meikle (Ed), Humana Press, Totowa NJ, 329-341, 1999. Tenover JL: Male Senescence. IN: Male Reproductive Function C. Wang (ed).Kluwer Academic Pub., Boston, MA , Tenover JL: Topical Review: Testosterone replacement therapy in older adult men. Int J Androl. 22:300-306 (1999). Tenover, JL: Benign prostatic hyperplasia/urinary obstruction. IN: Kelley's Textbook of Internal Medicine. HD Hume (ed). 4th edition. Lippincott, William & Wilkins, Philadelphia, 3085-3090, 2000. JL: HRT for the aging male: A therapy that has come of age? IN: The Testis From Stem Cell to Sperm Function. E. Goldberg (ed). Springer-Verlap. New York, 82-88, 2000. Tenover JL: Risks and Benefits of Testosterone in Older Men. IN: Andrology in the 21st Century. B. Robaire, H. Chemes, CR Morales (eds). Medimond Medical Publications, Englewood, NJ, 395-405 (2001). JL: Hormone Replacement Therapy for Men. IN: Reproductive Medicine in the Twenty-First Century. DL Healy, GT Kovacs, R McLachlan, O Rodriquez-Armas (eds). Parthenon Publishing Group, Boca Raton FL. 383-389 (2001). Morales A, Tenover JL: Androgen deficiency in the aging male (ADAM): When, who and how to investigate and treat. Urol Clin N Amer 29(4), 975-982 (2002). JL: The Androgen-Deficient Aging Male: Current Treatment Options. Reviews in Urology, Vol 5, Suppl 1 JL: Testosterone and the Older Man. IN: Endocrine Replacement Therapy in Clinical Practice. AW Meikle (ed). Humana Press, Totowa, NJ, 397-414 (2003). JL: Androgens in Older men. IN: Androgens in Health and Disease. CJ Bagatell, WJ Bremner (eds). Humana Press, Totowa NJ, 347-364 (2003). Tenover JL: Trophic Factors and Male Hormone Replacement. IN: Principles of Geriatric Medicine & Gerontology. WR Hazzard, JP Blass, JB Halter, JG Ouslander, ME Tinetti (eds). McGraw-Hill, New York NY, 1325-1337 (2003). 31. Tenover JL: Androgens and Reproductive Aging. Book Review. J Androl 28: 27 (2007). Tenover JL: Testosterone Replacement Therapy and the Prostate. Current Sexual Health Reports 4: 79-82 (2007). Hsiao W, Tenover JL, Ritenour CWM. The role of testosterone replacement therapy in contemporary urological practice. AUA Update Series, American Urological Assn, Education and Research,inC., Linthicum MD, Vol 27, Lesson 40, 385-395 (2008). JL. Sexuality, Sexual Function, Androgen Therapy and the Aging Male. IN: Hazzard's Geriatric Medicine & Gerontology., 6th Edition. JB Halter, JG Ouslander, ME Tinetti, S Studenski, KP High, A Asthana (eds). McGraw-Hill, New York NY; 595-606 (2009). Myers JS, and Charon D: Derivatives of glycoproteins: Chemical modification of the component of human alpha-1 acid glycoprotein. Red Proc 35: #480, April Bremner WJ, Gross KM, Myers JS, and Matsumoto AM: Neuroendocrine aspects of reproduction in men. Internat Soc Androl, May l985. Myers JS, Matsumoto AM, and Bremner WJ: Reduced testosterone response despite normal hormone response to clomiphene in elderly men. Second NIADDK Symposium of the Study of Benign Prostatic Hyperplasia, May l985. JS, Matsumoto AM, and Bremner WJ: Episodic luteinizing hormone secretion and testosterone responses to clomiphene citrate in normal young and elderly men. Clin Matej LA, Bremner WJ, and Plymate SR: Diurnal and age-related changes in testosterone, sex hormone-binding globulin, and calculated free testosterone. First International Symposium on Binding Proteins: Steroid Hormones. April l986. Myers JS, Matsumoto AM, and Bremner WJ: Basal and clomiphene citrate stimulated secretion of luteinizing hormone and testosterone in healthy young and elderly men. Clin Res. 34: 430A, l986. Tenover JS, Matsumoto AM, Dahl KD, Lim P, Hseuh AJW, and Bremner WJ: Serum immunoreactive follicle-stimulating hormone (FSH) levels in healthy young and elderly men. Clin Res. 35: 124A, l987. JS, Plymate SR, Matsumoto AM, and Bremner WJ: The effect of aging in normal men on "bioavailable testosterone". The Endocrine Society (69th Annual Meeting), #869, l987. Rivier J, Vale W, and Bremner WJ: Comparative effectiveness of "Nal-GLu", a new LHRH antagonist, in normal young and elderly men. Clin Res. 38: 128A, l988. McLachlan RI, Tenover JS, Matsumoto AM, deKretser DM, and Bremner WJ: Decreased serum inhibin levels in normal elderly men: Evidence for decreased Sertoli cell function with aging. Clin Res. 38: 125A, l988. Matsumoto AM, Clifton DK, and Bremner WJ: Changes in the circadian rhythm of luteinizing hormone (LH) secretion with aging in normal men. Clin Res.38: 98A, l988. Bremner WJ, Tenover JS, Matsumoto AM, McLachlan RI, and Plymate SR: Endocrine aspects of the aging human testis. Eighth International Congress of Endocrinology, l988. McLachlan RI, Burger HG, and deKretser DM: Decreased serum inhibin levels in men: Evidence for a decline in Sertoli cell function with aging. The Endocrine Society (70th Annual Meeting), Zeitner ME, and Plymate SR: Effects of 24-week administration of a 5-alpha reductase inhibitor (MK-906) on serum levels of testosterone (T), free T, and gonadotropins in men. The Endocrine Society (71st Annual Meeting), #583, l989. JS.: Effect of testosterone (T) replacement on parameters of bone turnover in aging Workshop Conference on Androgen Therapy, January l990. Proscar Study Group. Treatment of benign prostatic hyperplasia (BPH) with Proscar, a 5 - reductase (5 a R) inhibitor. Workshop Conference on Androgen Therapy, January l990. Plymate SR, Jones RE, McLachlan RI, and Tenover JS: Decreased serum inhibin responses to infertile men with varicocele. J Androl. 11 (suppl): 21-P (#3), l990. Martens HF, Sheets PK, Tenover JS, Dugowson CE, Bremner WJ, and Starkebaum GA: Primary testicular failure in male rheumatoid arthritis (RA) patients. Arthritis Rheum 33 (Suppl): S21, 1990. J: Circadian rhythm of serum immunoreactive inhibin in elderly and young adult men. Society (73rd Annual Meeting), # 439, 1991. Tenover JS: Effect of testosterone (T) and 5 -reductase inhibitor (5-ARI) administration on the sexual function questionnaire in older men. J Androl . 13 (Suppl): P-50 (#129), J, Matsumoto AM: Effect of testosterone (T) on growth hormone (GH) and insulin-like 1 (IGF-1) levels in healthy elderly and young adult men. The Endocrine Society (74th Annual Meeting ), #366,1992. JS, Matsumoto AM, Naai SR, Sanders SW, Caramelli K, Mazer NA: Non-scrotal transdermal delivery of testosterone (T) to elderly androgen deficient men. Amer Soc Androl, #A19, 1993. JS, Androgen Replacement in Aging Men. The Endocrine Society (78th Annual Reagan J, Byrnes C, Liss C, Tenover, JL, Uppert M, Gillenwater J. Efficacy and tolerability of Proscar (Finasteride) in middle-aged and older men with symptomatic BPH: Combined analysis of two clinical trials. American Urological Association (92nd annual meeting), #554, 1997. Kaplan S, Short K, Geller J, Tenover L, Brader B et al. Baseline symptoms determine long-term response to finasteride: results of four-year placebo controlled trial. European Association of Urology Congress, P30, March, 1998. Holtgrewe L, Bruskewitz R, Stanley G, Peterson L, Tenover L, Ercole C, Sussman DO, Auerbach S, Soloway M, Johnson E, Wang D, Pappas F. Observations on the natural history of BPH in men followed in a four-year placebo- controlled trial. American Urological Association 93rd Annual meeting, Abs# 396, J. Urol 159(3):103,1998. Roy J, Bannow J, Grayhack J, Matzumoto A, Tenover L, Herling R, Rous S et al. Long-term experience with finasteride in treatment of BPH: Sexual adverse experiences are similar between treated and placebo groups after the first year of therapy. American Urological Association 93rd Annual meeting, Abs# 1279, J. Urol 159(3): 333,1998. Tenover JL. Androgen deficiency in aging men. Abstracts of the First World Congress on the Aging Male. The Aging Male, Vol 1 (suppl 1), 1998, Abs #S07. JL, O'Grady M, Wolf SL, Ortiz S, Aviles X, Puttlitz K, Hysni C, Sandborn M. Effect of different resistance training programs on lower extremity strength and muscle soreness in previously untrained adults. Gerontological Society of America 52nd Annual Scientific Meeting, Abs #1605, San Francisco, 1999. JL. Special considerations for androgen replacement in older men. The Endocrine Society (82nd Annual Meeting), B-41, June 2000. O'Grady M, Tenover JL, Getz P, Wolf S. Can body composition changes detect muscle power in aging, androgen-deficient men who are transitioning towards fraility?, American Geriatrics Society Annual Meeting, P, May 2001 O'Grady MO, Tenover JL, Getz P, Grossman J. Lawson AM, Wolf SL. Power training and testosterone supplementation in older androgen deficient men. VIIth International Congress of Andrology, P5/6-082, June 2001. Amory JK, Watts NB, Easley KA, Sutton PR, Anawalt BD, Matsumoto AM, Bremner WJ, JL. Testosterone (T) plus finasteride for 3 years increases bone mineral density without volume in older men with low serum T. 28th Annual Meeting of the American Society of Andrology, Abs #10, March 2003. Page ST, Amory JK, Bowman FD, Anawalt, BD, Matsumoto AM, Bremner WJ, Tenover JL. or testosterone with finasteride increases physical performance, grip Strength, and lean body mass in older men with low serum testosterone. 12th International Congress of Endocrinology, Lisbon, Portugal, Abs #P692, September 2004. Page ST, Amory JK, Matsumoto AM, Tenover JL. Exogenous testosterone (T) alone or with finasteride increases physical performance, grip strength, and lean body mass in older men with low serum T. Western Section American Federation for Medical Research, Carmel CA, Abs #115, February 2005. Vaughan C, Goldstein F, Tenover L. Exogenous testosterone (T) alone or with finasteride does not improve measurement of cognition in healthy older men with low serum T. American Geriatrics Society Annual Meeting, #P43, May 2006.

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