TREATING LIKE ALIKE: THE PRINCIPLE OF NON- DISCRIMINATION AS A TOOL TO MANDATE THE EQUAL TREATMENT OF REFUGEES AND BENEFICIARIES OF COMPLEMENTARY PROTECTION [Recent years have seen academics in the field of international law demonstrate a growing interest in the subject of complementary protection, particularly in the rights that follow from complementary protection as opposed to from refugee status. While scholars have largely focused on the ‘protection gap' between the rights granted to refugees and those granted to beneficiaries of complementary protection in the context of international law, they often overlook the fact that this ‘gap' is most significant at a domestic level. They also overlook the potential usefulness of the principle of non-discrimination codified under art 26 of the International Covenant on Civil and Political Rights as a way to close the ‘protection gap' between the two groups. This paper seeks to promote art 26 as a valuable tool for the elimination of differentiation between refugees and beneficiaries of complemen-tary protection, thereby enhancing its role as a source of rights for highly vulnerable individuals and enriching the way we think about entitlement to protection at international law.]
Title pageThis is the full-text of the pre-print version.
1. Title of the article. The Effectiveness of Acupuncture for Plantar Heel Pain: a systematic review. Full name, postal address, e-mail, telephone and fax numbers of the corresponding Richard J Clark BSc, MBBS, LicAc, DipMedAc Peninsula College of Medicine and Dentistry, C206 Portland Square, Drake Circus, PLYMOUTH, PL4 8AA, UK Richard@IntegrativeHealthcare.co.uk Tel: 01752 691415 Fax: 01752 691415 3. Full names, departments, institutions, city and country of all co-authors. Maria Tighe PhD, SCHPN(HV), RGN School of Nursing and Midwifery, Faculty of Health, Education and Society, Plymouth University, 7 Portland Villas, PL4 8AA, UK 4. Up to five keywords or phrases suitable for use in an indexterms). Acupuncture Therapy Fasciitis, Plantar Trigger Points Electroacupuncture Laser Therapy, Low-Level 5. Word count - excluding title page, abstract, references, figures and tables. ABSTRACT
Introduction: Plantar heel pain (PHP) is a common complaint, yet there are no definitive guidelines for its treatment. Acupuncture is increasingly used by podiatrists, and there is a need for evidence to validate this practice. It is acknowledged that both PHP and acupuncture are complex phenomena. Method: A systematic review (PROSPERO no. CRD42012001881) of the effectiveness of acupuncture for PHP is presented. Quality of the studies was assessed by independent assessors with reference to Quality Index (QI), STRICTA and CONSORT criteria. Pooling of data, or even close comparison of studies, was not done. Results: Five RCTs and 3 non-randomised comparative studies were included. High quality studies report significant benefits. In one, acupuncture was associated with significant improvement in pain and function, when combined with standard treatment (including NSAIDs). In another, acupoint PC7 improved pain and pressure pain threshold significantly more than LI4. Other papers were of lower quality but suggest benefits from other acupuncture approaches. Conclusion: There is evidence supporting the effectiveness of acupuncture for PHP. This is comparable to the evidence available for conventionally used interventions, such as stretching, night splints or dexamethasone. Therefore acupuncture should be considered in recommendations for the management of patients with PHP. Future research should recognise the complexity of PHP, of acupuncture and of the relationship between them, to explore the optimum use and integration of this approach. There is a need for more uniformity in carrying out and reporting such work and the use of STRICTA is recommended. MAIN TEXT
Plantar heel pain (PHP) is one of the most common foot problems and is responsible for substantial morbidity and financial burden.[1-4] An array of pathologies can give rise to pain beneath the heel, including vascular, neurologic, arthritic and malignant aetiologies; once such conditions are excluded, what remains is PHP. Typical findings include pain on taking the first few steps in the morning, pain that increases with weight bearing, and pain and tenderness upon palpation of the medial calcaneal tubercle. Historically, PHP has been referred to as ‘plantar fasciitis' (PF) and some authors also use the term ‘calcaneal spur'. The accuracy of such terms has been contested and they are beginning to be replaced by others, such as ‘plantar fasciosis'. However, even this term is inappropriate here, as it embodies the assumption that the plantar fascia is the seat of the problem. The aetiology of PHP is complex, involving the interplay of tissue, biomechanical, psychological and other factors. These are modelled in different ways by acupuncturists (e.g. myofascial trigger points, or disturbances of ‘Qi') and, as Sackett et al point out, the practitioner perspective is an important aspect of the Evidence Based Practice (EBP) triad. Therefore an inclusive approach was adopted for this paper (see methods and discussion sections). Conventionally many different interventions are used, yet the evidence for their use is inconclusive.[9-12] Compliance is often poor and interventions such as non-steroidal anti-inflammatory drugs (NSAIDs) and steroid injections carry significant risks.[14-15] Recently, increasing numbers of podiatrists are incorporating acupuncture into their practices and initial results seem favourable. Anecdotally, alumni of a training programme validated by the Society of Chiropodists and Podiatrists report good results from incorporating acupuncture into their approaches. Meanwhile the body of published work in this area is increasing. Thus it is now appropriate to conduct a rigorous assessment of the role acupuncture might play in the management of PHP. An earlier systematic review addressed a related question, considering dry needling and injections of myofascial trigger points (MTPs) associated with plantar heel pain. Recognising (from clinical experience) that many patients suffer from PHP in the absence of MTPs, the current authors chose to review studies drawing on a wider range of types of acupuncture practice. Thus, the research question was: "what is the evidence regarding the effectiveness of acupuncture for PHP?" This paper presents a systematic review of publications relating to this question, discusses the implications, and makes suggestions for future development. Safety was not considered in this review; this aspect has been studied more appropriately elsewhere.[19-22] The protocol was registered with PROSPERO (no. CRD42012001881). Recognising the heterogeneity in the reporting of this phenomenon, a broadly inclusive search strategy was chosen to identify relevant work. A comprehensive literature search was carried out as follows. The databases searched were: PubMed, AMED (EBSCO), British Nursing Index, CINAHL plus (EBSCO), EMBase, MEDLINE (EBSCO), MEDLINE (Ovid), Oxford Journals, PsychARTICLES, ScienceDirect, SocINDEX (EBSCO), SwetsWise, Taylor & Francis Online, Wiley Online Library. The search parameters included All Dates (from inception to the end of 2011), All Types of publication, All Languages, and All Fields. The precise wording of the searches varied in different databases, using different thesauri. The general principle was to include ‘Acupuncture' OR ‘dry needl*' OR ‘Trigger Points' OR ‘moxibustion' OR ‘TENS' OR ‘laser therapy' AND ‘heel pain' OR ‘plantar fasci*' OR ‘heel spur' OR ‘calcan*'. The search was extended by following all relevant leads in sources read. Reference lists of papers obtained were scanned for further relevant papers. Journals identified were searched electronically where possible, or by scanning tables of contents. Leads were also obtained from available textbooks, online forums and the internet and personal communications. Titles and abstracts were scanned to identify papers for inclusion. Papers relating to PHP and related diagnoses were included; those relating to pain secondary to other pathologies,[24,25] or to experimental pain in animal subjects were excluded. Papers were included if they described the use of acupuncture, acupuncture points, TCM or moxibustion. Papers describing the use of MTPs were included if the treatment was (dry) needling, whether or not an acupuncture-related rationale was used. Papers describing the use of laser therapy or transcutaneous electrical nerve stimulation (TENS) were included only if the therapy was applied specifically to acupuncture points, or if an acupuncture-related rationale was used. Randomised Controlled Trials (RCTs) and non-randomised comparative studies were included. Case series, single case studies and secondary reports were excluded from this review but will be considered in detail elsewhere (Clark & Tighe, in preparation). Two papers were translated.[27,28] Data were extracted into a spreadsheet, as summarised in Tables 1a-1c. Assessment of the standards of reporting was carried out using CONSORT (for RCTs) and STRICTA and quality of the studies was assessed using the Quality Index. To enable comparison, the QI scale was modified as recommended by Cotchett (however, only one paper appeared in both studies, so meaningful comparison was impossible). The two authors rated each paper independently; scores were discussed to identify and resolve differences, and so achieve consensus. Percentage scores were calculated in relation to the number of relevant items, to enable comparison across the scales. Further quality data were extracted, as summarised in Table 2. Narrative summarisation was performed; neither data synthesis nor meta-analysis was possible. RESULTS AND DISCUSSION OF STUDIES
The search identified 342 potentially relevant articles (see Fig. 1), of which 8 met the inclusion criteria: 5 RCTs,[27-28,32-34] 2 non-randomised comparative studies[35-36] and 1 cohort study using "patients as their own controls". Flow chart for selection of papers
332 records identified 10 records identified through through searches 287 records excluded on basis of title & abstract 5 articles unobtainable 50 full text articles assessed for eligibility 4 articles excluded (not acupuncture or not PHP) 23 articles excluded (secondary sources or non-clinical) 15 articles excluded (case studies or case series) 8 articles included in systematic review (5 RCTs, 3 comparative studies) A summary of the papers is provided in Tables 1a to 1c: Table 1a – Higher quality trials*
Results / Conclusions
Plantar Fasciitis (Gp 2) Up to 12 painful (Gp 1) standard tmt Both groups improved significantly, al, 2011
Duration >2wk (mean 16.1d) and other points including: ice, extensive fasciitis pain scale chosen from a list of stretching program and – Willis et al) At wk 8 improvement = Mean age 37.1 18 classical acupoints. Gp1 26%, Gp2 47%; P<0.05 No prior treatments Slight rotation and Minor adverse effects noted thrusting to elicit deqi (dull, numb or heavy) Retained 20-30 min, with "periodic manual stimulation". 16 sessions, 2/wk. Plus standard treatment as Gp1. Zhang et al,
Plantar fasciitis (diagnosed (Gp 2) LI4, contralateral Significantly greater improvement 2009 DBRCT
as ‘pain localized to the contralateral to pain. in Gp1 than Gp2 at 4 data points. medial tubercle of the Depth 10 mm. Activity pain (AP), Significant decrease in MP (from Deqi elicited each 5 Deqi elicited each 5 min; Overall pain (OP) baseline) seen in Gp1 at 1, 3 and Duration > 3mo (3-216 mo) Retai ned 30 min. Retained 30 min. 6mo f-u (P<0.001). Both groups Pressure algometry showed significant decreases in AP Age >18 (mean 48.5) and OP. Gp2 non-significant Various prior treatments improvement in MP. session and follow- Negative correlation found between up at 1, 3 & 6 mo prior duration of complaint and improvement. One drop-out due to needling pain at LI4. * These two trials scored higher than all the others in terms of quality of trial and of reporting, as indicated by QI, STRICTA & CONSORT scores (see Table 2). ** In original papers, acupoints were named according to different conventions; where necessary, these have been translated to the WHO recommended format (eg. the point Xiaguan is rendered as ST7). Abbreviations used: DBRCT, double blind randomised controlled trial; deqi, the characteristic feeling produced by the needle; f-u, follow- up; Gp, group; NSAID, non-steroidal anti-inflammatory drug; P, probability value; pt, point; tmt, treatment. Table 1b – Other randomised controlled trials
Results / Conclusions
Liu et al, 2010
‘Calcaneus spur' (on XR) (Gp 2) "common acupuncture" - Both gps PRR >50%. Duration 4-38mo Even method, deqi to GB34, BL60, BL57, KI3. PRR of over 60% for 64.7% Gp1, 37.5% Gp2 P<0.05. Age 31-64 Retained 20 min. Asserts safe, but without giving Prior treatments not Daily, 30 sessions walking function, during 3 courses of 10. swelling, burning Plus pyrogenic herbal Orellana Molina
Heel spur (but diag (Gp 2) Acupuncture to (Gp 1) Point application of infra- Gp1: Cure 11/26; Improved 15/26 et al, 1996
ahshi, BL40, BL60, KI3, red laser (904 nm) to ahshi, at sessions 3, 6, Gp2: Cure 16/26, Improved 10/26 Duration not stated o Also Gp2: Onset of benefit Rotate at start & at 16J/cm2 to ahshi, 7J/cm2 to sooner; fewer pts required 2nd Age <40 to >60 Prior treatments not Daily x10, repeat if necessary. Daily x10, repeat if Not improved = > 5 Vrchota et al,
Plantar fasciitis Gp 2 - 'Sham acupuncture': Mean pain score >50% less. Sig Duration not stated sham points on sole, minimal diff. True > sham > sports Gender not stated Electroacupuncture to depth, subthreshold score, decided by medicine (including NSAID drug) Age not stated KI1, KI3, Ahshi; Pain log showed more relief in Prior treatments not 5/80 Hz, to tolerance. stretches, footwear advice, patient, each on Gp1 than Gp3 at wk 4 (P=0.010) Retained 20 min. and follow-up (P=0.016). Plus calf stretches, Gp 3 - 'sports medicine Pain score showed more relief in footwear advice, therapy', including reduced until 3w after last Gp1 than Gp3 at wk 4 (P=0.014). training, stretches, ice and Tenderness scores changed little. NSAID. Plus footwear advice, Activity log (data Abbreviations used: ahshi, the point of maximum tenderness; DBRCT, double blind randomised controlled trial; deqi, the characteristic feeling produced by the needle; Gp, group; NSAID, non-steroidal anti-inflammatory drug; P, probability value; pt, point; RCT, randomised controlled trial; sig diff, significant difference. Table 1c – Non-randomised studies
Results / Conclusions
Chen & Zhao,
Heel pain, mostly non- (Gp 1) Steroid + LA 3 groups comparable - no sig diff. specific +/- calcaneal spurs. Depth 0.3-0.5 cun local pt, x5-6 in 3wk; complete resolution Acupuncture group: Duration 3 mo - 30 yr Good = remarkable Excellent 15/50, comparative case 10 sessions, daily, (Gp 2) As Gp1 plus Aged <30 to >70 during two weeks Poor = no response Poor 15/50 [allowing for typo] Prior treatments not stated. plus herbs as in Gp 2 decoction b.d. x15 Follow-up 1-8yr (mean 3.5) Ouyang & Yu,
‘Pain in the sole' (including Gp 1: ST7, Ipsilateral. Gp 2: 'corresponding' Depth 1.5 cun; palmar pt, Ipsilateral. 97.1 (Gp1); 92.6 (Gp2); 100 (Gp3) Duration 1-6mo (N=14); MR = marked relief comparative clin >1yr (N=29); 3yr (N=1); rest counter-clockwise; PR = partial relief Concludes combination is more not stated. Retain 20-30 min. clockwise; NR = no relief effective, but palmar points often Daily x5 per course Retain 20-30 min. painful, so use latter only if ST7 fails. Age 30-78 Daily x5 per course Prior treatments not stated. Gp 3: both ST7 and response rate (RR). Tillu & Gupta,
Plantar fasciitis ‘Classical acupoints' Trigger points (calf and Significant reduction from baseline in Duration 12-30mo plantar) added if needed VAS % change; Prospective case for sessions 5-6. verbal rating score wk 4 [40.3%] (P<0.0009) and series with 'self- Mean age 49.17 (SD 10.66). Deqi sought (tingling ) wk 6 [69%] (P<0.0001). Previously unsuccessful Significant reduction between w4 and conservative treatment Retained 15 min. wk6 (P<0.047). (physiotherapy, shoe Concludes classical acupoints support, steroid injection) effective, enhanced by addition of trigger points in failed cases. Recommends use of MTP from the start. Abbreviations used: b.d., twice a day; cun, a standard measurement used in acupuncture practice; deqi, the characteristic feeling produced by the needle; Gp, group; LA, local anaesthetic; MTP, myofascial trigger points; P, probability value; pt, point; sig diff, significant difference. and quality assessment is summarised in Table 2 Table 2: Evaluation of trial reporting and trial quality
Applications and research centre, Military Medical present the satisfactory The parallel use of STRICTA, QI and CONSORT gave a multifaceted appreciation of the overall quality of the studies and their reporting. There was reasonable agreement between the rankings by the three instruments. Table 2 illustrates the wider quality issues of clinical and research ethics governance, revealing weak methodology in most of the papers. No papers declared their commissioning or peer review status (although three appeared in peer-reviewed journals). Only two declared funding received. Five papers appeared in acupuncture-focused journals; three studies took place in colleges of TCM. The relationship between clinical practice and research was often blurred (indicating potential for Hawthorne effect and social desirability bias) and there was a lack of transparency regarding ethical governance. However two papers[32,34] achieved high standards by most of these criteria and this is reflected in their high QI ratings. Individual papers
Karagounis et al assessed the value of adding acupuncture treatment to a standard
clinical approach, for men with acute PF. While the ‘standard' group showed improvement
(pain score reduced 26%), the acupuncture group improved almost twice as much (47%,
P<0.05). This is a high quality study with good internal and external validity, and well
reported. The treatment used was semi-individualised and the detail provided for the
acupuncture given is not enough for precise duplication of the process.
Zhang et al assessed the specific efficacy of acupoint PC7 (compared to LI4) for PF of
over 3 months duration. They concluded that PC7 gives a significantly greater benefit, at
1mo and 6mo follow-up. This trial scores well on internal validity, less so on external
One might criticise the choice of LI4 as a comparator, in that it is widely used to treat pain, including heel pain (e.g.). Conversely, this makes it ideal as a ‘control' treatment; if LI4's reputation is undeserved and it is, in fact, an inert intervention, then it serves as a demonstrably credible placebo; conversely, if it is an effective point, then PC7 has been shown to be even more so. Tillu & Gupta studied a series of 18 consecutive patients with PF of over a year
duration. All had failed to benefit from prior conservative treatments, including steroid
injection in 12 cases. Patients received acupuncture to ‘classical points' (KI3, BL60, SP6),
weekly for 4 weeks which resulted in significant improvement of mean VAS (Visual Analog
Scale) pain scores (P<0.0009). Two patients needed no further treatment; the remaining
16 were then given the same treatment twice more, with the addition of needling ‘trigger
points in the gastro-soleus and plantar fascia'. This resulted in a significant further
improvement (P<0.047). This was an uncontrolled and non-blinded study and so has low
scores on internal validity; also the quality of reporting is moderate by modern standards.
However the approach used is very relevant to clinical practice. The authors argue that
each patient served as their own comparator in view of the long duration of complaint, with
failure of prior treatments. Comparison is also possible between the two phases of the
study, however without concurrent control groups one can not eliminate change due to
Orellana Molina et al studied pain related to heel spurs, comparing the effectiveness
of laser treatment at acupoints with needling a similar group of points, chosen according to
the traditional ‘eight principles' approach. While both groups showed benefit, the laser
group reported improvement sooner and to a greater degree. Significance is claimed for
this result but (even after professional translation) the statistical method used is unclear.
Vrchota et al studied the efficacy of ‘True Acupuncture' (TA) compared to ‘Sham
Acupuncture' (SA) and to ‘Sports Medicine Therapy' (SMT) for PF in a Sports Medicine
Clinic. TA included the use of ahshi, local trigger points and classical acupoints, to which
electroacupuncture was applied at the level of tolerance. SA consisted of shallow needling
at two unrelated points on the sole, with minimal electroacupuncture (below threshold of
perception). The SMT group received advice to reduce training, apply ice, stretching
exercises and NSAID medication. Pain reduction was significantly greater in the TA group
than the SMT group after 4 treatments and 3 weeks later. The results in the SA group
were intermediate between the other two groups, but differences did not reach significance.
This paper lacks many details including: demographic characteristics, duration of
complaint, prior treatments and blinding. Thus TA appears more effective than SMT but
questions remain as to which aspects are important, and the possible confounding effect of
Liu et al studied the effectiveness of needling a single point (GB39) in conjunction with
local heat application via a herbal dressing, in comparison to ‘common acupuncture'
needling 4 other points, for patients with chronic pain related to heel spurs. Using a
combined ‘Points Reduction Rating' they found significantly greater improvement in the
‘GB39 plus heat' group ("marked improvement" in 64.7% compared to 37.5%; P<0.05).
This is described as a single blind study, with patients uninformed. No concealment of
treatment is described; it is assumed that patients were simply not informed that their
treatment was different from the ‘common' treatment. The ethics of this is not discussed.
The outcome measure used is a points score derived from subjective reporting. Variants of
this approach are common in Chinese clinical studies over the past few decades but no
validation is mentioned.
Ouyang & Yu studied patients with pain in the sole (including an unstated number in
the heel), comparing the use of ST7 with a ‘corresponding point' on the palm, or both of
these combined. (Corresponding point is assumed to mean a location on the palm
analogous to the pain location on the foot but this is not made explicit.) They conclude that
the combination is more effective, however the differences are small and unlikely to be of
statistical significance. This paper reports outcomes as clinical judgements of relief
obtained (complete, marked, partial, none) and, unlike comparable papers, combine the
first 3 into a global Response Rate. When ‘partial' is excluded (by the current authors, to
reflect more common practice) ST7 emerged as more effective than the Palmar point (76.5
cf 59.3%). Furthermore, needling the palm was found to be too painful for some patients,
so the recommendation was to use ST7 as first choice and reserve palmar needling for
unresponsive cases. This approach is not widely known in the West, and challenges the
professional boundaries of some practitioners (eg. podiatrists, who would not normally
needle the face) yet the response rates reported here seem promising.
Chen & Zhao retrospectively reported an extensive series of patients with heel pain.
They compared the results of 50 receiving acupuncture to BL61 (plus an individualised
herbal decoction), with 102 receiving steroid injection into tender point (plus herbal
decoction), and with 748 receiving steroid alone (5-6 injections during 3 weeks). They
stated that there was no significant difference between the ‘effective rate', which averaged
73.5% in the three groups. The statistical method used is not stated and, on close
inspection of their data, the numbers in the table do not add up to the totals given, so it is
impossible to draw a conclusion from this.
A systematic search identified 8 papers providing evidence regarding the effectiveness of acupuncture for PHP. Two studies provide good reporting of high quality studies; 6 are of lesser quality. All report positive outcomes however they are heterogeneous in several ways, making it difficult for simple conclusions to be drawn. Heterogeneity
The STRICTA scores achieved by these papers range from 46.9 to 94.1%. This is
unsurprising because 5 of them were published before the STRICTA guidelines were
available. The highest scores were obtained by the three most recent papers. Future
studies should be more rigorous in adhering to these guidelines.
The indication for treatment is variously stated as heel pain (although one paper is less
precise), plantar fasciitis (but the definitions differ) or heel spur (with or without XR
confirmation). The problem of diagnostic labelling for heel pain was discussed above.
Authors of the papers reviewed showed variable awareness of the shortcomings of these
terms. The assumptions underlying such labels are now seen to be incorrect, yet it is likely
that they influence the design of treatments. For example, if the focus is on ‘inflammation',
then acupoints thought to influence inflammation may be chosen; meanwhile a potentially
more useful approach (e.g. treating MTPs) may be overlooked.
An earlier systematic review focused exclusively on MTPs. While this has the merit of
simplicity, it may not reflect a reality which is complex. This review has shown that MTPs
may give additional benefit when added to classical acupuncture but also that
acupuncture unrelated to MTPs confers significant benefits. Clinical experience (RJC)
shows that some patients have MTPs related to their heel pain and others do not; there is a
need to explore the possibility that these are two pathologically distinct groups, requiring
different treatment approaches.
Prior duration of the complaint, where stated, varied between 2 days and 30 years. This is
perhaps of particular significance in that one paper noted an inverse correlation
between duration and benefit obtained, which suggests that it would be prudent to control
for duration in future studies.
The gender ratio also varied. In most papers it was between 26.4 and 43.8% male, which
is comparable to the distribution of heel pain in the general population. However one
study included only male patients, which may be a significant confounding factor;
recent papers highlight effects of patient or practitioner gender on perceptions of pain and
The outcome measures vary from precise, prospective use of relevant pain scales (VAS, PFPS (Plantar fasciitis pain scale)) to retrospective clinical judgements. All assessed subjective pain, some assessed function and one assessed tenderness objectively. Perhaps the greatest difference between these papers is the treatment approach used – although all studies involve acupuncture, none of them use the same approach. This should remind us that acupuncture is not a unitary intervention, indeed it is very complex. Limitations of this paper
As a practising acupuncturist, the present author (RJC) might be biased in favour of a positive outcome. Any such bias should be apparent, if not neutralised, by the transparency and systematic nature of this review. Publication bias Positive outcomes Five of the papers reviewed were published in acupuncture journals, with unknown peer-review standards, so it seems likely that there is a bias in favour of positive findings, particularly as they date back as far as 1985. However the two higher quality papers were published in peer-reviewed non-acupuncture journals, so we place more confidence in them. It is impossible to know if there were similar studies with negative outcomes that remain unpublished. Positivist methodology Including RCTs but excluding case studies, imposes a bias towards formulaic (rather than individualised) approaches. This fails to reflect the reality of practice. Sackett notes the importance of this: "Evidence based medicine … requires a bottom up approach that integrates the best external evidence with individual clinical expertise and patients' choice". At this point it is worth comparing the two high-scoring papers : Zhang et al is a rigorous and well-reported DBRCT, high on internal validity. However the interventions compared bear little relation to common practice, and the effect size is small. In contrast, Karagounis et al demonstrated a worthwhile level of effect, using a treatment approach which is much closer to real-world practice, and it scored well on external validity. Conclusions
In view of the heterogeneity of these papers, it is not possible to give a simple conclusion, in the form: X is shown (or not) to be efficacious for Y. A number of different approaches were identified, which indicate potential uses of acupuncture for treating heel pain, as summarised in Table 3: Table 3: Summary of findings
High quality studies have shown: o a part-individualised approach using up to 12 classical points gave significant improvements in pain and function, when added to standard treatment (including NSAIDs) o PC7 is significantly more effective than LI4 for medial heel pain and Less rigorous studies suggest that: o Electroacupuncture to local points (classical, ahshi and MTPs) gives significantly more benefit than Sports Medicine Treatment (including NSAIDs) o Infrared laser stimulation of BL40 + BL60 + Ahshi seems more effective than needling BL40 + BL60 + KI3 + KI6 o Needling GB39 plus local heated herbal dressing gives significantly more benefit than needling GB34 + BL57 + BL60 + KI3 o Needling BL61 + individualised herbal decoction, is as effective as multiple steroid injections into Ahshi point (with or without the herbs) o Needling ST7 is as effective as (and more comfortable than) palmar points o In patients unhelped by prior treatments (including steroid injection) for 12 months, significant benefit was obtained by needling KI3 + BL60 + SP6, and this was enhanced by the addition of MTPs Thus there is evidence at level I and II supporting the effectiveness of acupuncture for heel pain, leading to a recommendation at Grade B. This is comparable to the evidence available for conventionally used interventions, such as stretching, night splints or dexamethasone. Therefore acupuncture should be included in recommendations for the treatment of PHP. Future research should avoid the simplistic question ‘Is acupuncture efficacious for heel pain?' and instead focus on exploring the optimum use of acupuncture for heel pain. The field is not yet ripe for RCT studies. We are currently at the ‘Development' stage as defined by the MRC – this paper is ‘identifying the evidence base' and the next two phases (2 Identifying/developing theory and 3 Modelling process and outcomes) are being addressed in a separate study. RJC carried out the searches, screened the papers, assessed quality, drafted and finalised the paper. MT collaborated in the design of the literature search strategy, provided independent assessment of bias and quality, discussed the findings, contributed to writing of the paper and agreed its final draft. We are grateful for the generous support of various people: the librarians at the University of Westminster, Plymouth University and the Open University. Translations were carried out by Ding Renxiang and by RJC with the help of Arantxa and Ismael Arinas Pellon. Help in obtaining some papers was received from Anthony O'Reilly (Department of Foot Health, Derbyshire County PCT) and from Laura Gearing (Department of Foot Health, Southwark PCT). Critical commentary on a draft of the paper was received from: Emma Cowley and Mark Price. DECLARATION OF INTEREST
RJC offers training courses on the use of acupuncture for podiatrists and other health professionals. This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors. REFERENCES
1. Riddle DL, Schappert SM. Volume of ambulatory care visits and patterns of care for patients diagnosed with plantar fasciitis: a national study of medical doctors. Foot
Ankle Int. 2004;25:303-10.
2. Riddle DL, Pulisic M, Sparrow K. Impact of demographic and impairment-related variables on disability associated with plantar fasciitis. Foot Ankle Int. 2004;25:311-
3. Tong KB, Furia J. Economic burden of plantar fasciitis treatment in the United States. Am J Orthop 2010;39:227-31.
4. Scher D, Belmont PJ, Bear R, et al. The Incidence of Plantar Fasciitis in the United States Military. J Bone Joint Surg Am 2009;91:2867-72. doi:10.2106/JBJS.I.00257.
5. Scher D, Belmont PJ, Owens B. The epidemiology of plantar fasciitis. Lower Extremity Review 2010 http://www.lowerextremityreview.com/article/the-epidemiology-of-plantar-fasciitis. Accessed 22/2/2012. 6. Bartold SJ. The plantar fascia as a source of pain—biomechanics, presentation and treatment J Bodyw Mov Ther 2004;8:214-26.
7. Sorensen MD, Hyer CF, Philbin TM. Percutaneous Bipolar Radiofrequency Microdebridement for Recalcitrant Proximal Plantar Fasciosis. J Foot Ankle Surg
8. Sackett DL, Rosenberg WM, Gray JAM, et al. Evidence based medicine: what it is and what it isn't - It's about integrating individual clinical expertise and the best external
evidence. BMJ 1996;312:71-2.
9. Landorf KB, Menz H. Plantar heel pain and fasciitis. Clin Evid 2008; http://ukpmc.ac.uk/abstract/MED/19450330. Accessed 22/2/2012. 10. McPoil TG, Cornwall MW, Wukich DK, et al. Heel Pain-Plantar Fasciitis: clinical practical guidlelines. J Orthop Sports Phys Ther 2008;38:A1-A18.
11. Donley BG, Moore T, Sferra J, et al. The efficacy of oral nonsteroidal anti-inflammatory medication (NSAID) in the treatment of plantar fasciitis: a randomized, prospective,
placebo-controlled study. Foot Ankle Int. 2007;28:20-3.
12. Thomas JL, Christensen JC, Kravitz SR, et al. The Diagnosis and Treatment of Heel Pain: A Clinical Practice Guideline–Revision 2010. J Foot Ankle Surg 2010;49:S1-
13. Walter JHJ. Heel Pain Treatments Stretch Patients' Tolerance. BioMechanics 2001; http://www.coachr.org/heelpain.htm. Accessed 22/2/2012. 14. NSAIDs and adverse effects. Bandolier 2007; 15. Tatli YZ, Kapasi S. The real risks of steroid injection for plantar fasciitis, with a review of conservative therapies. Curr Rev Musculoskelet Med 2009;2:3-9.
16. A Guide to Podiatry. 2008; http://www.feetforlife.org/search/?q=A+Guide+to+Podiatry. Accessed 22/2/2012. 17. Anwar R. An Evaluation Of Acupuncture Treatment In A Podiatry Clinic. 2003; 18. Cotchett MP, Landorf KB, Munteanu SE. Effectiveness of dry needling and injections of myofascial trigger points associated with plantar heel pain: a systematic review. J
Foot Ankle Res 2010;3:18.
19. Rampes H, James R. Complications of acupuncture. Acupunct Med 1995;13:26-33.
20. White A. A cumulative review of the range and incidence of significant adverse events associated with acupuncture. Acupunct Med 2004;22:122-33.
21. Witt CM, Pach D, Reinhold T, et al. Treatment of the adverse effects from acupuncture and their economic impact: A prospective study in 73,406 patients with low back or
neck pain. Eur J Pain 2010;15:193-97.
22. Zhao L, Zhang F, Li Y, et al. Adverse events associated with acupuncture: three multicentre randomized controlled trials of 1968 cases in China. Trials 2011;12:87-
23. Clark RJ, Tighe M. The use of acupuncture for heel pain: a systematic review PROSPERO 2012; CRD42012001881 http://www.crd.york.ac.uk/prospero/display_record.asp?ID=CRD42012001881. Accessed 16/1/2012. 24. Smith SR. Acupuncture in the treatment of tarsal tunnel syndrome. Journal of Chinese Medicine 2009;89:19-25.
25. Woodrow SL, Brereton-Smith G, Handfield-Jones S. Painful piezogenic pedal papules: response to local electro-acupuncture. Br J Dermatol 1997;136:628-30.
26. Mao-Ying QL, Cui KM, Liu Q, et al. Stage-dependent analgesia of electro-acupuncture in a mouse model of cutaneous cancer pain. Eur J Pain 2006;10:689-94.
27. Orellana Molina A, Hernández Díaz A, Larrea Cox PJ, et al. [Láser infrarrojo frente a acupuntura en el tratamiento del espolón calcáneo]. Revista de la Sociedad Espana
del Dolor 2010;17:69-77.
28. Liu MY, Nie RR, Chi ZH, et al. [Observation on therapeutic effect of acupuncture at Xuanzhong (GB 39) combined with Chinese herbs pyrogenic dressing therapy for
treatment of calcaneus spur]. Zhongguo Zhen Jiu 2010;30:189-91.
29. CONSORT: transparent reporting of trials. 2011; www.consort-statement.org. Accessed 14/7/11. 30. MacPherson H, Altman DG, Hammerschlag R, et al. STRICTA 2010: STandards for Reporting Interventions in Clinical Trials of Acupuncture. 2010; http://www.stricta.info/. Accessed 22/2/2012. 31. Downs S, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non- randomised studies of health
care interventions. J Epidemiol Community Health 1998;52:377-84.
32. Karagounis P, Tsironi M, Prionas G, et al. Treatment of Plantar Fasciitis in Recreational Athletes. Foot Ankle Spec 2011;4:226-34. doi:10.1177/1938640011407320.
33. Vrchota K, Belgrade M, Johnson R, et al. True acupuncture vs. sham acupuncture and conventional sports medicine therapy for plantar fascitis pain: a controlled, double-
blind study International Journal of Clinical Acupuncture 1991;2:247-53.
34. Zhang SP, Yip TP, Li QS. Acupuncture Treatment for Plantar Fasciitis: A Randomized Controlled Trial with Six Months Follow-up. Evid Based Complement Alternat Med
35. Chen BX, Zhao YL. Treatment of painful heel with combined method of traditional Chinese medicine and western medicine. Clinical analysis of 900 cases. Chin Med J
36. Ouyang Q, Yu G. Acupuncture at upper limb points for pain of the sole: a report of 73 cases. International Journal of Clinical Acupuncture 1996;7:499-501.
37. Tillu A, Gupta S. Effect of Acupuncture Treatment on Heel Pain due to Plantar Fasciitis. Acupunct Med 1998;16 66-68.
38. Price MJ. Getting to the point! A case history. British Journal of Podiatry 2002;5:50-2.
39. Choi PYL, Tweed A. The holistic approach in acupuncture treatment: Implications for
clinical trials. J Psychosom Res 1996;41:349-56. doi:10.1016/s0022-
40. Yin CS, Park J, Lee J-Y, et al. Acupuncture perception (deqi) varies over different points and by gender with two distinct distribution patterns of dullness and pain.
Journal of Sensory Studies 2009;24:635-47. doi:10.1111/j.1745-459X.2009.00229.x.
41. Lund I, Lundeberg T. Is it all about sex? Acupuncture for the treatment of pain from a biological and gender perspective. Acupunct Med 2008;26:33-45.
42. Willis B, Lopez A, Perez A, et al. Pain Scale for Plantar Fasciitis. Foot & Ankle Online Journal 2009; http://faoj.org/2009/05/01/pain-scale-for-plantar-fasciitis/. Accessed 22/2/2012. 43. Paterson C, Britten N. Acupuncture as a complex intervention: a holistic model. J Altern Complement Med. 2004;10:791-801.
44. CEBM. Levels of Evidence (March 2009). 2011; http://www.cebm.net/index.aspx?o=1025. Accessed 17/1/2012. 45. MRC. Complex interventions guidance. 2008;
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Guías de Práctica Clínica Obstetricia Sindicato de Ginecología y Obstetricia Guías de Práctica Clínica Sindicato de Ginecología y Obstetricia SOGOS Introducción:. 3 Medicina Basada en la Evidencia: . 3 Guía de práctica clínica de Cesárea:. 5 Guía de Práctica clínica de Ruptura Prematura de Membranas Ovulares . 14 Guía de Práctica Clínica de Embarazo Prolongado . 28