Untitled
Information Sheet
Hallucinations and
Parkinson's
What are hallucinations?
When a person hallucinates they may see, hear, feel,
It seems that the hallucinations are caused partly by
smell or taste something that, in reality, does not exist.
Parkinson's itself and partly by the medication that is
prescribed to treat it. While just about any of the drugs
While most people with Parkinson's disease do not
can be to blame, hallucinations are more likely to affect
get hallucinations, some people may experience
people who take dopamine agonist and anticholinergic
hallucinations and these are usually visual. While the
drugs, particularly if they are in the older age group.
hallucinations may comprise quite complex scenes,
Further information about these drugs is available in
they typically involve the person seeing small animals,
the Parkinson's Disease Society (PDS) booklet
The Drug
insects or other people in the room with them. These
Treatment of Parkinson's Disease.
images do not usually speak or make sounds and they
can either disappear quickly or last for some time.
Sometimes, hallucinations occur when an adjustment has
Occasionally, the hallucinations are auditory (where the
been made to the dose of a particular anti-Parkinson's
person hears a voice or sound without seeing anything),
drug or when a new drug is added to a combination
or tactile (the person feels something touching them),
that the person is already taking. On other occasions,
but for people with Parkinson's, these are less common
it seems that the hallucinations occur spontaneously,
than visual hallucinations.
without any immediate cause.
Sometimes, people with Parkinson's experience
It is important to remember that most people who have
delusions of presence; when they feel that an animal
Parkinson's take their medication successfully, without
or object is present just next to them but they do not
experiencing hallucinations. You should not, therefore,
actually see it.
be put off taking the drugs that are prescribed for you.
If you are worried or have questions about the medication
Most people with Parkinson's fi nd that the hallucinations
you are taking, you should discuss these with your GP,
they experience are not threatening or distressing. In many
specialist doctor or Parkinson's Disease Nurse Specialist.
cases, the person with Parkinson's is actually aware that
You can also call the Society's freephone Helpline
the images or sounds are not real, and are able to cope
(0808 800 0303) to talk to a nurse adviser.
with them. In fact, some people even look upon the
person or object that they see as a companion. In other
instances, the hallucinations can be very frightening,
Sometimes, hallucinations are not simply due to
particularly if the person with Parkinson's believes that
Parkinson's or its drug treatment, but are precipitated
the image they see or sound they hear is real and do not
by some other cause. For example, an acute illness
realise that they are, in fact, hallucinating. In such cases,
such as a bladder or chest infection can cause people
coping with hallucinations can be diffi cult.
to hallucinate, as can some medications that are
prescribed to treat other conditions. Hallucinations can
What causes hallucinations?
also be a feature of dementia.
The hallucinations associated with Parkinson's can
affect both younger and older people, but they are more
common in the older age group, and particularly in
Occasionally, visual hallucinations may be due to
those who have had Parkinson's for a long time.
severely impaired vision. See the PDS information sheet
Parkinson's and Eyes for more information.
Contact the Parkinson's Disease Society
s Disease Society fr
eephone helpline for advice and information on
freephone helpline for advice and information on 0808 800 0303
How are hallucinations treated?
Treatment with special drugs
If you are experiencing hallucinations, it is important that
The type of drug that is often prescribed to treat
you visit your doctor so that the cause can be identifi ed
hallucinations is called a neuroleptic or antipsychotic
and any appropriate treatment given.
drug. Unfortunately, most of these drugs can make the
symptoms of Parkinson's worse. There are two types
Treat any underlying illness
– the older, conventional ones and newer, atypical drugs.
If there is some other underlying cause, such as a
Older, more conventional neuroleptics, such as
bladder infection, the doctor will treat this and the
haloperidol (trade name Haldol) and chlorpromazine
hallucinations should then disappear.
(Largactil), always markedly worsen parkinsonism.
Thioridazine (Melleril) and sulpiride (Dolmatil) cause
Adjustment of anti-Parkinson's medication
moderate worsening. The newer, atypical neuroleptics
If the hallucinations are associated with Parkinson's
are so called because they are less likely to cause side
but are not troublesome, the doctor may decide to
effects than standard antipsychotic drugs.
delay giving treatment and just monitor the situation.
If, however, the hallucinations are causing distress to
However, at least two of these drugs, risperidone
the person with Parkinson's, the doctor may suggest
(Risperdal) and olanzapine (Zyprexa), should be used
that some treatment is necessary.
with caution to treat dementia in people at risk of stroke
(the risk increases with age, hypertension, diabetes,
The fi rst line of treatment is usually to adjust the anti-
atrial fi brillation, smoking and high cholesterol), because
Parkinson's medication. This will involve a reduction in
of an increased risk of stroke and other cerebrovascular
the dose, or the gradual withdrawal, of particular drugs.
problems. It is unclear whether there is an increased
The doctor will usually withdraw anticholinergic drugs,
risk of stroke with quetiapine (Seroquel) and clozapine
particularly in older people, and other drugs may also be
(Clozaril). Quetiapine (Seroquel) seems much less
reduced. Such measures can often eliminate or reduce
prone to worsen Parkinson's symptoms and is often
the hallucinations, and any improvement is usually noticed
used to treat hallucinations, especially when they are
within a few weeks, or sometimes even within a few days.
accompanied by troublesome delusions. Clozapine
Unfortunately, making adjustments to the anti-
(Clozaril) also usually does not worsen Parkinson's
Parkinson's drugs does not always eliminate the
symptoms, but can be associated with serious bone
hallucinations. In addition, you may fi nd that a reduction
marrow toxicity. It is, therefore, only used in special
in the dose, or the withdrawal, of some drugs can
circumstances, and with close monitoring through
mean that the symptoms of Parkinson's are not as well
regular blood tests.
controlled as they were before. In these cases, the
The potential risks of any drug treatment will need to
doctor will usually try to achieve a balance by reducing
be balanced against the diffi culties that might ensue if
the hallucinations to an acceptable level while, at the
nothing is done.
same time, trying to maintain a good level of control
over the Parkinson's symptoms. This compromise
Cognitive impairment and Parkinson's
is usually acceptable if the hallucinations are not
Hallucinations may arise, either on or off anti-Parkinson's
distressing and the Parkinson's symptom control is
drug treatment, in people with Parkinson's who
relatively good. If a satisfactory balance between
already have some degree of cognitive impairment (for
hallucinations and symptoms cannot be achieved, the
example, poor recent memory), often associated with
doctor may consider prescribing a special drug to help
fl uctuating alertness and arousal (sometimes falling
overcome the problem.
asleep after taking their tablets). In this situation, drugs
Contact the Parkinson's Disease Society freephone helpline for advice and information on 0808 800 0303
called cholinesterase inhibitors such as donepezil
important to encourage the person with Parkinson's to
hydrochloride (Aricept), rivastigmine (Exelon) and
discuss the hallucinations with their doctor because it is
galantamine (Reminyl) may improve both cognitive and
likely that something can be done to help.
behavioural problems and often also hallucinations.
These drugs can sometimes worsen Parkinson's tremor.
Where can I obtain further information?
Increasingly, Parkinson's specialists are more likely to
If you or the person you are caring for is experiencing
consider rivastigmine as the drug of choice for treating
hallucinations, the best person to advise you is your GP
hallucinations, especially if there is co-existent dementia.
or consultant. It is important that you visit the doctor
so that the cause of the hallucinations can be identifi ed
Caring for someone who experiences
and any appropriate treatment given.
If you have access to a Parkinson's Disease Nurse
Hallucinations can be very diffi cult for a carer to cope
Specialist, it is likely that they will be able to provide
with. It is not always easy to know how to react and
you with further advice about coping with hallucinations.
what to say to someone who is hallucinating.
The PDS is also here to help you. If you have any
While the hallucinations can be quite distressing for the
questions or require further information, please contact
carer, it is important to try to stay calm. Do not agree
us. Our Helpline number is 0808 800 0303, available
that there is something in the room when there is not
Monday–Friday, 9.30am–9pm, Saturday, 9.30am–5.30pm
and try not to let an argument develop about whether
(except bank holidays).
the image or sound is real. Instead, offer reassurance,
particularly if the hallucinations are causing distress to
The PDS would like to thank Dr Duncan Forsyth,
Dr Ronald Pearce and Dr Hugh Rickards for their help
It is sometimes helpful to explain that you cannot see
with updating this information sheet.
what they are seeing or hear what they are hearing,
but you understand that the images and sounds are
very real to them. It can also be effective to distract
the person in order to take their mind off what they are
seeing. The image may then disappear. Of course, it is
Parkinson's Disease Society
215 Vauxhall Bridge Road, London SW1V 1EJ, UK
Tel: 020 7931 8080
Fax: 020 7233 9908
Helpline: 0808 800 0303
Parkinson's Disease Society of the United Kingdom (2008)
Charity registered in England and Wales No. 258197 and in Scotland No. SCO37554.
A company limited by guarantee. Registered No. 948776 (London)
Registered offi ce: 215 Vauxhall Bridge Road, London SW1V 1EJ
Revised March 2008
To obtain any PDS resource, please go online to www.parkinsons.org.uk or contact Sharward Services Ltd,
the appointed PDS Distribution House, at Westerfi eld Business Centre, Main Road, Westerfi eld,
Ipswich, Suffolk IP6 9AB, tel: 01473 212115, fax: 01473 212114, email:
[email protected]
Contact the Parkinson's Disease Society freephone helpline for advice and information on 0808 800 0303
Source: http://www.parkinsonportal.gr/download.php?s=LyJ5lQ
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