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Primary Palmar Hyperhidrosis
Topical antiperspirant therapy
Iontophoresis using tap water
(aluminium and zirconium salts)
Pay special attention to
Educate re-application time/technique
correct techique, device,
to maximise efficacy and
water mineral content,
minimise side effects.
and patient education/training.
response & able to
Specialist management for hyperhidrosis
Westside Dermatology in conjunction
with Queensland Vascular Group
Onabotulinumtoxin A injections
Adjust technique, frequency, duration
water mineral content. Consider adding
anticholinergics to water.
Repeat P.R.N.
response & able to
Make adjustments to technique,
dose and/or area covered.
Consider systemic medications:
1. Anticholinergics
Repeat P.R.N.
(eg. glycopyrrolate,
oxybutynin, propantheline)
No response and in carefully
cases are idiopathic, however the
selected and educated patients
condition maybe secondary to
who fully understand the risks
and complications of ETS
drugs, neurological disorders or
including, but not limited to,
To maximise efficacy and
systemic diseases.
minimize side effects,
consider combination therapy
Endoscopic thoracic sympathectomy
adjusted to patient needs and
The Sweat Free Clinic is
WHAT INVESTIGATIONS
ARE NEEDED FOR PALMAR
Australia's first multidisciplinary
specialist clinic
In most patients this condition is primary and idiopathic, and no investigations are needed. Primary
Sweat Free Clinic is comprised of
issue discusses the management
hyperhidrosis typically has an
dermatologists, vascular surgeons
options for sweaty palms, or palmar
onset before puberty, is bilateral
and specialist nurse practitioners
and symmetrical, and does not
who manage all aspects of
occur during sleep. It is often focal,
excessive sweating.
and involves areas such as the
BOTOX Treatment is now available under
Sweat Free Clinic
Hyperhidrosis is a common condition hands, feet, underarms or face.
Specialist PBS listing for the management
Westside Dermatology
Over the next 6 months we will
that afflicts 3% of the population.
Secondary hyperhidrosis is usually
of severe underarm sweating.
185 Moggill Road, Taringa. 4068
cover management options for
The most commonly involved areas
asymmetrical, of late onset, and
• Patients entitled to 3 treatments per annum
plantar, axillary, generalized,
include the hands, feet, axillae, and
often generalized.
• Botox lasts on average 6.1 months• Costing to patients equivalent to $2 per day
and facial hyperhidrosis. This first
face. The majority of hyperhidrosis
Non-surgical options for the
Endoscopic Thoracic Sympathectomy
Management of Palmar Hyperhidrosis
for Palmar Hyperdidrosis
Dr Andrew Cartmill
MBBS, FACD Consultant Laser Dermatologist
B.Sc., M.B.B.S. (Hons), F.R.A.C.S. (Vasc)
Vascular and Endovascular Surgeon
applied on a nightly basis and
can be ionized. Sweat production
washed off in the morning. The
is reduced via dysfunction of the
In many cases, symptoms of palmar
compensatory hyperhidrosis in other
find it much less debilitating than
rate-limiting factor is skin irritation.
eccrine gland. Iontophoresis is
hyperhidrosis are relatively mild and regions of the body, which is a risk
the palmar symptoms prior to
This over the counter topical should
considered to be third line therapy
are well controlled without the need
particularly with higher T2 ganglion
treatment. Provided patients are well
always be applied to dry skin. Ask
failing topical and oral medications.
for surgery. In more severe cases
transection. The lung is reinflated
informed through a comprehensive
patients to use a hairdryer on ‘cool'
It can be effective in up to 70% of
or after failure of medical therapy,
over a drain tube, which is removed pre-operative discussion about
settings to evaporate sweat prior to
palmar-plantar hyperhidrosis.
patients are often considered for
on the first post-operative morning
expectations, this risk is not a
minimally-invasive endoscopic
prior to discharge home.
major concern. Other risks include
thoracic sympathectomy (ETS). The
small pneumothoraces which
Failing iontophoresis I usually
ETS is a very well-tolerated
aim is to reduce the sympathetic
spontaneously resolve, bleeding,
Primary palmar hyperhidrosis usually Anticholinergics such as
compound creams or wipes
procedure which carries a success
outflow the palms whilst preserving
infection and Horner's syndrome.
presents in late childhood and is
Propanthelene Bromide can reduce
containing Glycopyrrolate. Once
rate for eliminating palmar
other sympathetic nerve functions.
This last risk can be caused by
most often bilateral and symmetrical. palmar, plantar and axillary
again, as per anticholinerics,
hyperhidrosis of over 90%. The
interruption of the T1 (Stellate)
Sweat production ranges from mild
sweating. Start patients on 15mg
systemic side-effects limits the use.
This is achieved through 2 small
main risk to be considered is
gangion and is therefore a very rare
to very severe. Palmar hyperhidrosis
nocte, increase as tolerated to
intercostal incisions beneath the
the chance of ‘compensatory
can affect schooling, and work,
❘❘ Botox injections
a maximum of 45 mg per day.
armpit for endoscopic access to
hyperhidrosis' which may occur in
and has a significant impact on
The use of Botulinumtoxin A has
Anticholinergic side effects such
the chest cavity. Unilateral lung
25-50% of cases. As expected,
There is usually minimal pain aside
relationships and self-confidence.
been approved by the PBS for the
as sedation can be seen in up to
deflation is performed under general not all sympathetic outflow can
from some transient generalised
management of severe axillary
anaesthesia, to facilitate exposure of be eliminated, and compensatory
chest discomfort and surgical site
Treatment options
80% of cases, however if tolerated,
hyperhidrosis not responding to
oral medication can be considered
the sympathetic chain on each side.
sweating particularly in the chest
pain. These both rapidly subside.
❘❘ Avoidance of triggers
Driclor, however BOTOX can
For palmar hyperhidrosis, the aim is
and abdomen can occur. Usually
Patients can expect to be in hospital
Decreasing trigger factors for
as second line management.
be used off label for palmar
the interruption of the T3 ganglion
this is mild, well-tolerated, and
for 1 night after the procedure,
sweating, including caffeine and
A combination of Driclor and
hyperhidrosis. In this setting I use
only by direct division of the chain.
much less severe than the palmar
and usually return to work duties,
energy drinks can improve mild
anticholinergics can reduce
this treatment as the last resort prior
This will prevent sympathetic signals
sweating the procedure was
schooling and regular activities
palmar hyperhidrosis, however has
sweating to an acceptable level in
to the consideration of surgery.
to the hands to reduce sweating,
originally performed for. Indeed
within a few days.
little impact on severe cases.
one third of palmar hyperhidrosis
Unlike it's use in the axillary vault,
whilst minimising the likelihood of
most patients who develop this
side effects such as transient muscle
❘❘ AntiperspirantsDriclor or Aluminium Chloride
❘❘ Iontophoresis
weakness can be seen, additionally
Hexahydrate 20% is first line
This procedure is conducted in clinic efficacy is limited to 3-4 months in
Referrals to:
management and can be
and involves passing of an ionized
this area, compared to 6-7 months
Sweat Free Clinic
successful in mild cases of palmar
substance through intact skin. The
for axillary sweating. Non-PBS listing
Westside Dermatology
hyperhidrosis. This should be
most common medium is tap water,
also adds costs to the patient.
185 Moggill Road, Taringa. 4068
however compounded solutions
P 3871 34 37F 38711570
Source: http://www.miradry.com.au/sites/default/files/info-download/SFC_Newsletter_Aug12_V4.pdf
GUÍA DE SEGUIMIENTO DE LOS PACIENTES Laura Tuneu Valls Miquel Rojas Cano Montse Sardans Marquillas Elisa Paredes Pérez Correo Farmacéutico ha cedido los derechos depublicación de la guía "SeguimientoFarmacoterapéutico de los pacientes conAlzheimer" que obtuvo el máximo galardón en elSegundo Premio en Atención Farmacéutica.
Osteoporos IntDOI 10.1007/s00198-011-1528-y Skeletal mineralization defects in adulthypophosphatasia—a clinical and histological analysis F. Barvencik & F. Timo Beil & M. Gebauer & B. Busse &T. Koehne & S. Seitz & J. Zustin & P. Pogoda & T. Schinke &M. Amling Received: 14 April 2010 / Accepted: 3 January 2011 # International Osteoporosis Foundation and National Osteoporosis Foundation 2011